Published: Nature
Date:
Authors: NCD Risk Factor Collaboration (NCD-RisC)
Abstract:
High blood cholesterol is typically considered a feature of wealthy western countries1,2. However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world3 and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health
Published: The New England Journal of Medicine
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Authors: Aaron S Kelly 1 , Pernille Auerbach 1 , Margarita Barrientos-Perez 1 , Inge Gies 1 , Paula M Hale 1 , Claude Marcus 1 , Lucy D Mastrandrea 1 , Nandana Prabhu 1 , Silva Arslanian 1 , NN8022-4180 Trial Investigators
Abstract:
Background: Obesity is a chronic disease with limited treatment options in pediatric patients. Liraglutide may be useful for weight management in adolescents with obesity.
Published: Diabetes Care
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Authors: William I Sivitz 1 , Lawrence S Phillips 2 3 , Deborah J Wexler 4 , Stephen P Fortmann 5 , Anne W Camp 6 , Margaret Tiktin 7 , Magalys Perez 6 , Jacqueline Craig 8 , Priscilla A Hollander 9 , Andrea Cherrington 10 , Vanita R Aroda 11 , Meng Hee Tan 12 , Jonathan Krakoff 13 , Neda Rasouli 14 , Nicole M Butera 15 , Naji Younes 15 , GRADE Research Group
Abstract:
We evaluated the effect of optimizing metformin dosing on glycemia and body weight in type 2 diabetes.
Published: The Lancet Global Health
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Authors: NCD Risk Factor Collaboration (NCD-RisC)—Americas Working Group
Abstract:
Describing the prevalence and trends of cardiometabolic risk factors that are associated with non-communicable diseases (NCDs) is crucial for monitoring progress, planning prevention, and providing evidence to support policy efforts. We aimed to analyze the transition in body-mass index (BMI), obesity, blood pressure, raised blood pressure, and diabetes in the Americas, between 1980 and 2014.
Published: Diabetes Care
Date:
Authors: Deborah J Wexler 1 , Heidi Krause-Steinrauf 2 , Jill P Crandall 3 , Hermes J Florez 4 , Sophia H Hox 5 , Alexander Kuhn 6 , Ajay Sood 7 , Chantal Underkofler 8 , Vanita R Aroda 6 , GRADE Research Group
Abstract:
GRADE (Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study) is a 36-center unmasked, parallel treatment group, randomized controlled trial evaluating four diabetes medications added to metformin in people with type 2 diabetes (T2DM).
Published: Global Heart
Date:
Authors: Juan P González-Rivas 1 , Jeffrey I Mechanick 2 , Eunice Ugel 3 , María Inés Marulanda 4 , Maritza Duran 5 , Ramfis Nieto-Martínez 6
Abstract:
Cardiovascular health status of the Venezuelan population has not been evaluated. The American Heart Association recommends the Cardiovascular Health Score (CHS) to assess cardiovascular health.
Published: The New England Journal of Medicine
Date:
Authors: William V Tamborlane, Margarita Barrientos-Pérez, Udi Fainberg, Helle Frimer-Larsen, Mona Hafez, Paula M Hale, Muhammad Y Jalaludin, Margarita Kovarenko, Ingrid Libman, Jane L Lynch, Paturi Rao, Naim Shehadeh, Serap Turan, Daniel Weghuber, Timothy Barrett, Ellipse Trial Investigators
Abstract:
Metformin is the regulatory-approved treatment of choice for most youth with type 2 diabetes early in the disease. However, early loss of glycemic control has been observed with metformin monotherapy. Whether liraglutide added to metformin (with or without basal insulin treatment) is safe and effective in youth with type 2 diabetes is unknown.
Published: Journal of Comparative Effectiveness Research
Date:
Authors: Stephanie Behringer-Massera 1 , Terysia Browne 2 , Geny George 3 , Sally Duran 3 , Andrea Cherrington 4 , M Diane McKee 2 5 , GRADE Research Group
Abstract:
Recruitment of participants into research studies, especially individuals from minority groups, is challenging; lack of diversity may lead to biased findings.
Published: Endocrine Practice
Date:
Authors: Ramfis Nieto-Martínez, Juan P González-Rivas, Eunice Ugel, Imperia Brajkovich, Alejandro Risquez, W Timothy Garvey, Jeffrey I Mechanick
Abstract:
To determine the prevalence of obesity according to the American Association of Clinical Endocrinologists/American College of Endocrinology (AACE/ACE) framework based on a complications-centric model with further application of the Cardiometabolic Disease Staging (CMDS) system in a Venezuelan population.
Published: Current Diabetes Reports
Date:
Authors: Ramfis Nieto-Martínez 1 2 3 , Juan P González-Rivas 4 , José R Medina-Inojosa 5 , Hermes Florez 6 7
Abstract:
Eating disorders (ED) affect energy intake modifying body fat depots. Prior evidence suggests that binge eating disorder (BED) and bulimia nervosa (BN) could increase the risk for type 2 diabetes (T2D), while anorexia nervosa (AN) could reduce it.