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Facilitators and barriers to successful recruitment into a large comparative effectiveness trial: a qualitative study

Published: Journal of Comparative Effectiveness Research
Date:
Authors: Stephanie Behringer-Massera 1 , Terysia Browne 2 , Geny George 3 , Sally Duran 3 , Andrea Cherrington 4 , M Diane McKee 2 5 , GRADE Research Group

LINK TO RESEARCH
https://pubmed.ncbi.nlm.nih.gov/31368793/

ABSTRACT
Background: Recruitment of participants into research studies, especially individuals
from minority groups, is challenging; lack of diversity may lead to biased
findings. Aim: To explore beliefs about research participation among individuals who were
approached and eligible for the GRADE study. Methods: In-depth qualitative telephone interviews with randomized participants (n
= 25) and eligible individuals who declined to enroll (n = 26). Results: Refusers and consenters differed in trust and perceptions of risk,
benefits and burden of participation. Few participants understood how
comparative effectiveness research differed from other types of trials;
however, some features of comparative effectiveness research were perceived
as lower risk. Conclusion: We identified facilitators and addressable barriers to participation in
research studies.

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