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External validation of the Finnish diabetes risk score in Venezuela using a national sample: The EVESCAM

By December 1, 2019September 24th, 2020No Comments


Primary Care Diabetes

Ramfis Nieto-Martínez 1 ,
Juan P González-Rivas 2 ,
Eunice Ugel 3 ,
Maria Ines Marulanda 4 ,
Maritza Durán 5 ,
Jeffrey I Mechanick 6 ,
Pablo Aschner 7

Aims: To evaluate the performance of the Latin American Finnish Diabetes Risk
Score (LA-FINDRISC) compared with the original O-FINDRISC in general
population. To establish the best cut-off to detect unknown type 2 diabetes
(uT2D) and prediabetes.
Methods: The EVESCAM was a national population-based, cross-sectional, randomized
cluster sampling study, which assessed 3454 adults from July 2014 to
January 2017. Those with self-report of diabetes were excluded; a total of
3061 subjects were analyzed. Waist circumference adapted for Latin America
was the difference between the LA-FINDRISC and the O-FINDRISC. The area
under the curve (AUC), sensitivity, and specificity were calculated.
Results: The prevalence of uT2D and prediabetes were 3.3% and 38.5%. The AUC with
the LA-FINDRISC vs. the O-FINDRISC were: for uT2D, 0.722 vs. 0.729 in men
(p=0.854) and 0.724 vs. 0.732 in women (p=0.896); for prediabetes (impaired
fasting glucose [IFG] + impaired glucose tolerance [IGT], 0.590 vs. 0.587
in men (p=0.887) and 0.621 vs. 0.627 in women (p=0.777); for IFG, 0.582 vs.
0.580 in men (p=0.924) and 0.607 vs. 0.617 in women (p=0.690); for IGT,
0.691 vs. 0.692 in men (p=0.971) and 0.672 vs. 0.671 in women (p=0.974).
Using the LA-FINDRISC, the best cut-offs to detect uT2D were 9 in men and
10 in women and to detect IGT was 9 in both genders.
Conclusion: LA-FINDRISC has similar performance than O-FINDRISC in Venezuelan adults
and showed a good performance to detect uT2D and IGT, but not IFG. The best
cut-offs to detect glucose alterations were established.


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