The Canagliflozin and Renal Endpoints in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) Study Rationale, Design, and Baseline Characteristics

Published: American Journal of Nephrology
Date:
Authors: Meg J Jardine 1 2 , Kenneth W Mahaffey 3 , Bruce Neal 1 4 5 6 , Rajiv Agarwal 7 , George L Bakris 8 , Barry M Brenner 9 , Scott Bull 10 , Christopher P Cannon 11 , David M Charytan 12 , Dick de Zeeuw 13 , Robert Edwards 10 , Tom Greene 14 , Hiddo J L Heerspink 13 , Adeera Levin 15 , Carol Pollock 16 , David C Wheeler 17 , John Xie 10 , Hong Zhang 18 , Bernard Zinman 19 , Mehul Desai 10 , Vlado Perkovic 1 , CREDENCE study investigators
Abstract:
People with diabetes and kidney disease have a high risk of cardiovascular events and progression of kidney disease. Sodium glucose co-transporter 2 inhibitors lower plasma glucose by reducing the uptake of filtered glucose in the kidney tubule, leading to increased urinary glucose excretion.

Identification and management of prediabetes: results of the Latin America Strategic Prediabetes Meeting

Published: Pan American Journal of Public Health
Date:
Authors: Patricio López-Jaramillo 1 , Ramfis E Nieto-Martínez 2 , Gestne Aure-Fariñez 3 , Carlos O Mendivil 4 , Rodolfo A Lahsen 5 , Ruy L Silva-Filho 6 , Luiz A Andreotti 7 , Mónica E Manrique 8 , Miguel A Pasquel-Andrade 9 , Ignacio Rangel 10 , Maricela Vidrio 11 , Rutila Castañeda 12 , Manuela Restrepo 13 , Miguel E Pinto 14
Abstract:
To understand the status of prediabetes diagnosis and treatment in Latin America and to evaluate the use of metformin for diabetes prevention in this context.

Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults

Published: The Lancet
Date:
Authors: NCD Risk Factor Collaboration (NCD-RisC)
Abstract:
Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to obesity in children and adolescents, and to compare trends with those of adults.

Are Eating Disorders Risk Factors for Type 2 Diabetes? A Systematic Review and Meta-analysis

Published: Current Diabetes Reports
Date:
Authors: Ramfis Nieto-Martínez 1 2 3 , Juan P González-Rivas 4 , José R Medina-Inojosa 5 , Hermes Florez 6 7
Abstract:
Eating disorders (ED) affect energy intake modifying body fat depots. Prior evidence suggests that binge eating disorder (BED) and bulimia nervosa (BN) could increase the risk for type 2 diabetes (T2D), while anorexia nervosa (AN) could reduce it.

Transculturalizing Diabetes Prevention in Latin America

Published: Annals of Global Health
Date:
Authors: Ramfis Nieto-Martínez 1 , Juan P González-Rivas 2 , Pablo Aschner 3 , Noël C Barengo 4 , Jeffrey I Mechanick 5
Abstract:
Type 2 diabetes (T2D) imposes a heavy burden in developing countries, requiring effective primary prevention policies. Randomized clinical trials have identified successful strategies in T2D prevention. However, translating these results to real-life scenarios and adapting to ethnocultural differences is a major challenge.

Cardio-Metabolic Health Venezuelan Study (EVESCAM): Design and Implementation

Published: Invest Clin
Date:
Authors: Ramfis Nieto-Martínez, María Inés Marulanda, Juan P González-Rivas, Eunice Ugel, Maritza Durán, Noel Barengo, Pablo Aschner, Mario Patiño, Luis López Gómez, Pedro Monsalve, Héctor Marcano, Hermes Florez
Abstract:
LINK TO RESEARCH https://pubmed.ncbi.nlm.nih.gov/29939500/ ABSTRACT The EVESCAM (EstudioVenezolano de Salud Cardio-Metabólica) is the first national, population survey in Venezuela, designed to examine the prevalence of diabetes and cardio-metabolic risk factors...

Relationship between the Finnish Diabetes Risk Score (FINDRISC), vitamin D levels, and insulin resistance in obese subjects

Published: Primary Care Diabetes
Date:
Authors: Marcos M Lima-Martínez 1 , Carlos Arrau 2 , Saimar Jerez 2 , Mariela Paoli 3 , Juan P González-Rivas 4 , Ramfis Nieto-Martínez 5 , Gianluca Iacobellis 6
Abstract:
LINK TO RESEARCH https://pubmed.ncbi.nlm.nih.gov/27914905/ ABSTRACT Aim: To assess the relationship between 25-hydroxyvitamin D [25(OH)D] blood concentrations in subjects with obesity and type 2 diabetes mellitus (T2D) risk according to the...

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants

Published: The Lancet
Date:
Authors: NCD Risk Factor Collaboration (NCD-RisC)
Abstract:
Raised blood pressure is an important risk factor for cardiovascular diseases and chronic kidney disease. We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence of, and number of people with, raised blood pressure, defined as systolic blood pressure of 140 mm Hg or higher or diastolic blood pressure of 90 mm Hg or higher.

Transcultural Endocrinology: Adapting Type-2 Diabetes Guidelines on a Global Scale

Published: Endocrinology and Metabolism Clinics
Date:
Authors: Ramfis Nieto-Martínez 1 , Juan P González-Rivas 2 , Hermes Florez 3 , Jeffrey I Mechanick 4
Abstract:
Type-2 diabetes (T2D) needs to be prevented and treated effectively to reduce its burden and consequences. White papers, such as evidence-based clinical practice guidelines (CPG) and their more portable versions, clinical practice algorithms and clinical checklists, may improve clinical decision-making and diabetes outcomes