Cardiovascular Health in a National Sample of Venezuelan Subjects Assessed According to the AHA Score: The EVESCAM

Published: Global Heart
Date:
Authors: Juan P González-Rivas 1 , Jeffrey I Mechanick 2 , Eunice Ugel 3 , María Inés Marulanda 4 , Maritza Duran 5 , Ramfis Nieto-Martínez 6
Abstract:
Cardiovascular health status of the Venezuelan population has not been evaluated. The American Heart Association recommends the Cardiovascular Health Score (CHS) to assess cardiovascular health.

Liraglutide in Children and Adolescents with Type 2 Diabetes

Published: The New England Journal of Medicine
Date:
Authors: William V Tamborlane, Margarita Barrientos-Pérez, Udi Fainberg, Helle Frimer-Larsen, Mona Hafez, Paula M Hale, Muhammad Y Jalaludin, Margarita Kovarenko, Ingrid Libman, Jane L Lynch, Paturi Rao, Naim Shehadeh, Serap Turan, Daniel Weghuber, Timothy Barrett, Ellipse Trial Investigators
Abstract:
Metformin is the regulatory-approved treatment of choice for most youth with type 2 diabetes early in the disease. However, early loss of glycemic control has been observed with metformin monotherapy. Whether liraglutide added to metformin (with or without basal insulin treatment) is safe and effective in youth with type 2 diabetes is unknown.

Facilitators and barriers to successful recruitment into a large comparative effectiveness trial: a qualitative study

Published: Journal of Comparative Effectiveness Research
Date:
Authors: Stephanie Behringer-Massera 1 , Terysia Browne 2 , Geny George 3 , Sally Duran 3 , Andrea Cherrington 4 , M Diane McKee 2 5 , GRADE Research Group
Abstract:
Recruitment of participants into research studies, especially individuals from minority groups, is challenging; lack of diversity may lead to biased findings.

Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy

Published: The New England Journal of Medicine
Date:
Authors: Vlado Perkovic 1 , Meg J Jardine 1 , Bruce Neal 1 , Severine Bompoint 1 , Hiddo J L Heerspink 1 , David M Charytan 1 , Robert Edwards 1 , Rajiv Agarwal 1 , George Bakris 1 , Scott Bull 1 , Christopher P Cannon 1 , George Capuano 1 , Pei-Ling Chu 1 , Dick de Zeeuw 1 , Tom Greene 1 , Adeera Levin 1 , Carol Pollock 1 , David C Wheeler 1 , Yshai Yavin 1 , Hong Zhang 1 , Bernard Zinman 1 , Gary Meininger 1 , Barry M Brenner 1 , Kenneth W Mahaffey 1 , CREDENCE Trial Investigators
Abstract:
Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium-glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes.

Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Published: Nature
Date:
Authors: NCD Risk Factor Collaboration (NCD-RisC)
Abstract:
Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities1,2. This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity3-6

Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants

Published: International Journal of Epidemiology
Date:
Authors: NCD Risk Factor Collaboration (NCD-RisC)
Abstract:
Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population).

Prevalence of diabetes in three regions of Venezuela. The VEMSOLS study results

Published: Primary Care Diabetes
Date:
Authors: Ramfis Nieto-Martínez 1 , Jeffrey I Mechanick 2 , Imperia Brajkovich 3 , Eunice Ugel 4 , Alejandro Risques 5 , Hermes Florez 6 , Juan Pablo González-Rivas 7
Abstract:
The prevalence of diabetes in multiple regions of Venezuela is unknown. To determine the prevalence of diabetes in five populations from three regions of Venezuela.

APPLICATION OF THE AACE/ACE ADVANCED FRAMEWORK FOR THE DIAGNOSIS OF OBESITY AND CARDIOMETABOLIC DISEASE STAGING IN A GENERAL POPULATION FROM 3 REGIONS OF VENEZUELA: THE VEMSOLS STUDY RESULTS

Published: Endocrine Practice
Date:
Authors: Ramfis Nieto-Martínez, Juan P González-Rivas, Eunice Ugel, Imperia Brajkovich, Alejandro Risquez, W Timothy Garvey, Jeffrey I Mechanick
Abstract:
To determine the prevalence of obesity according to the American Association of Clinical Endocrinologists/American College of Endocrinology (AACE/ACE) framework based on a complications-centric model with further application of the Cardiometabolic Disease Staging (CMDS) system in a Venezuelan population.