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Are Eating Disorders Risk Factors for Type 2 Diabetes? A Systematic Review and Meta-analysis

By November 1, 2017September 24th, 2020No Comments


Current Diabetes Reports

Ramfis Nieto-Martínez 1 2 3 ,
Juan P González-Rivas 4 ,
José R Medina-Inojosa 5 ,
Hermes Florez 6 7

Recent findings: Eating disorders (ED) affect energy intake modifying body fat depots.
Prior evidence suggests that binge eating disorder (BED) and bulimia
nervosa (BN) could increase the risk for type 2 diabetes (T2D), while
anorexia nervosa (AN) could reduce it.
Purpose of review: A systematic review and meta-analysis were conducted to evaluate if ED are
risk factors for T2D. Ten studies were selected out of 1057 screened.
Meta-analysis of six studies with T2D as outcome is reported. Among
cross-sectional studies, both BED (OR 3.69, 95% CI [1.12-12.12]) and BN (OR
3.45 [1.92-6.1]) increased the risk of T2D, while AN was not associated
with lower risk (OR 0.87 [0.40-1.88]). Cohort studies showed increased risk
of T2D with BN (RR 1.7 [1.2-2.5]), and decreased risk with AN (RR 0.71
[0.52-0.98]), but for BED the association was less clear (OR 3.34
[0.85-13.12]). Limitations of studies and recommendations for future
research are presented.


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